Form of Proxy

REVOLUTION MEDICINES, INC.

BD Client Code:

Client Name:

Number of Shares Held in a BD Nominee Company:

No.	Proposition		For	Against	Abstain
1	DIRECTOR Alexis Borisy
2	DIRECTOR Mark A Goldsmith MD PhD
3	To ratify the appointment, by the Audit Committee of the Companys Board of Directors, of PricewaterhouseCoopers LLP, as the independent registered public accounting firm of the Company for its fiscal year ending December 31, 2026.
4	To approve, on a non-binding, advisory basis, the compensation of the Companys named executive officers as disclosed in the Proxy Statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission (Say-on-Pay).