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Form of Proxy

UNIQURE N.V.

Notes

No. Proposition For Against Abstain
1

Adoption of the 2025 Dutch statutory annual accounts for the fiscal year ended December 31, 2025.

2

Discharge of liability of the members of the Board for their management during the fiscal year ended December 31, 2025.

3

Reappointment of Madhavan Balachandran as non-executive director.

4

Reappointment of Jack Kaye as non-executive director.

5

Reappointment of Leonard Post, Ph.D. as non-executive director.

6

Designation of the Board as the competent body to issue Ordinary Shares and grant rights to subscribe for Ordinary Shares.

7

Designation of the Board as the competent body to exclude or limit preemptive rights upon the issuance of Ordinary Shares.

8

Reauthorization of the Board to repurchase Ordinary Shares.

9

Appointment of KPMG Accountants N.V. as external auditor of the Company for the fiscal year 2026.

10

Approval, on an advisory basis, of the compensation of the named executive officers of the Company.

11

Approval, on an advisory basis, of the frequency of advisory votes on the compensation of the named executive officers of the Company.

12

Resolution to adopt the Amendment and Restatement of the 2014 Share Incentive Plan.

13

Resolution to adopt the amendment to the Articles of Association to reflect Dutch large company regime.

14

Resolution to adopt the amendment to the Articles of Association to increase the authorized share capital and number of Ordinary Shares.

15

Resolution to adopt the amendment to the Articles of Association to include a federal forum selection provision.