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Form of Proxy

PRECISION BIOSCIENCES, INC.

Notes

No. Proposition For Against Abstain
1

DIRECTOR Melinda Brown

2

DIRECTOR Geno Germano

3

Ratification of the appointment of Deloitte & Touche LLP as Precisions independent registered public accounting firm for 2026.

4

Approval, on an advisory (non-binding) basis, of the compensation of our named executive officers (commonly referred to as the say-on-pay vote).

5

Approval of the amendment and restatement of the Companys 2019 Incentive Award Plan.

6

Approval of an amendment to our Certificate of Incorporation to reflect changes in Delaware law regarding officer exculpation.

7

Approval of an adjournment of the Annual Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Annual Meeting to approve any of the other proposals.