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Form of Proxy

TEMPUS AI, INC.

Notes

No. Proposition For Against Abstain
1

DIRECTOR Eric Lefkofsky

2

DIRECTOR Peter J. Barris

3

DIRECTOR Eric D. Belcher

4

DIRECTOR Jennifer A. Doudna

5

DIRECTOR David R. Epstein

6

DIRECTOR Wayne A.I. Frederick MD

7

DIRECTOR Scott Gottlieb, M.D.

8

DIRECTOR Theodore J. Leonsis

9

DIRECTOR Nadja West, M.D.

10

To ratify the appointment by the Audit Committee of the Board of Directors of PricewaterhouseCoopers LLP as the Companys independent registered public accounting firm for the fiscal year ending December 31, 2026.

11

To consider a non-binding advisory vote on the frequency of future stockholder votes to approve the compensation of the Companys named executive officers.