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Form of Proxy

CUE BIOPHARMA, INC.

Notes

No. Proposition For Against Abstain
1

Election of Director: Usman Azam

2

Election of Director: Pasha Sarraf

3

Election of Director: Peter A. Kiener

4

Election of Director: Frank Morich

5

Election of Director: Pamela Garzone

6

Election of Director: Patrick Verheyen

7

Election of Director: Jill Broadfoot

8

The ratification of the appointment of RSM US LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2026.

9

The approval, on a non-binding advisory basis, of the compensation of our named executive officers.

10

The adoption and approval of an amendment to our Amended and Restated Certificate of Incorporation, as amended, to effect a reverse stock split of our issued shares of common stock at a ratio within the range of not less than 1-for-30 and not more than 1-for-50, with the exact ratio within such range and the implementation and timing of such reverse stock split to be determined at the sole discretion of our board of directors without further approval or authorization of our stockholders.