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Form of Proxy

STERIS PLC

Notes

No. Proposition For Against Abstain
1

Election of Director: Dr. Esther M. Alegria

2

Election of Director: Richard C. Breeden

3

Election of Director: Daniel A. Carestio

4

Election of Director: Cynthia L. Feldmann

5

Election of Director: Christopher S. Holland

6

Election of Director: Paul E. Martin

7

Election of Director: Dr. Nirav R. Shah

8

Election of Director: Louis A. Shapiro

9

Election of Director: Dr. Mohsen M. Sohi

10

Election of Director: Dr. Richard M. Steeves

11

To ratify the appointment of Ernst & Young LLP as the Companys independent registered public accounting firm for the year ending March 31, 2026.

12

To appoint Ernst & Young Chartered Accountants as the Companys statutory auditor under Irish law to hold office until the conclusion of the Companys next annual general meeting.

13

To authorize the Board of Directors of the Company or the Audit Committee of the Board of Directors to determine the remuneration of Ernst & Young Chartered Accountants as the Companys statutory auditor under Irish law.

14

To approve, on a non-binding advisory basis, the compensation of the Companys named executive officers as disclosed pursuant to the disclosure rules of the U.S. Securities and Exchange Commission, including the compensation discussion and analysis and the tabular and narrative disclosure contained in the Companys proxy statement dated June 12, 2025.

15

To approve a proposal renewing the Board of Directors authority to issue shares under Irish law.

16

To approve a proposal renewing the Board of Directors authority to opt-out of statutory pre-emption rights under Irish law.