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Form of Proxy

JAZZ PHARMACEUTICALS PLC

Notes

No. Proposition For Against Abstain
1

Election of Director to hold office until the 2028 Annual General Meeting of Shareholders: Jennifer E. Cook

2

Election of Director to hold office until the 2028 Annual General Meeting of Shareholders: Patrick G. Enright

3

Election of Director to hold office until the 2028 Annual General Meeting of Shareholders: Seamus Mulligan

4

Election of Director to hold office until the 2028 Annual General Meeting of Shareholders: Norbert G. Riedel, Ph.D.

5

To ratify, on a non-binding advisory basis, the appointment of KPMG as the independent auditors of Jazz Pharmaceuticals plc for the fiscal year ending December 31, 2025 and to authorize, in a binding vote, the Board of Directors, acting through the audit committee, to determine KPMGs remuneration.

6

To approve, on a non-binding advisory basis, the compensation of Jazz Pharmaceuticals plcs named executive officers as disclosed in the proxy statement.

7

To grant the Board of Directors authority under Irish law to allot and issue ordinary shares for cash without first offering those ordinary shares to existing shareholders pursuant to the statutory pre-emption right that would otherwise apply.