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Form of Proxy

SUPERNUS PHARMACEUTICALS, INC.

Notes

No. Proposition For Against Abstain
1

Election of Director to hold office for the ensuing three years and until their successors have been duly elected and qualified: Carrolee Barlow, M.D., Ph.D.

2

Election of Director to hold office for the ensuing three years and until their successors have been duly elected and qualified: Jack A. Khattar

3

to approve, on a non-binding basis, the compensation paid to our named executive officers.

4

to ratify the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2025.

5

to consider and vote upon a stockholder proposal, if included in our Proxy Statement for the Annual Meeting of Stockholders (the Proxy Statement) and properly presented at the meeting.