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Form of Proxy

COMPASS PATHWAYS PLC

Notes

No. Proposition For Against Abstain
1

To re-elect as a director Thomas Lonngren, who retires by rotation in accordance with the Companys Articles of Association.

2

To re-elect as a director Robert McQuade, who retires by rotation in accordance with the Companys Articles of Association.

3

To re-elect as a director Kabir Nath, who retires by rotation in accordance with the Companys Articles of Association.

4

To re-elect as a director Gino Santini, who retires by rotation in accordance with the Companys Articles of Association.

5

To re-appoint PricewaterhouseCoopers LLP, an English registered limited liability partnership, as U.K. statutory auditors of the Company, to hold office until the conclusion of the next annual general meeting of shareholders.

6

To ratify the appointment of PricewaterhouseCoopers LLP (US) as the Companys independent registered public accounting firm for the fiscal year ending December 31, 2025.

7

To authorize the Audit and Risk Committee to determine the Companys auditors remuneration for the fiscal year ending December 31, 2025.

8

To receive the U.K. statutory annual accounts and reports for the fiscal year ended December 31, 2024 and to note that the Directors do not recommend the payment of any dividend for the year ended December 31, 2024.

9

To receive and approve on an advisory basis the Companys U.K. statutory directors remuneration report for the year ended December 31, 2024, which is set forth as Annex A to the attached proxy statement.

10

To approve, on a non-binding, advisory basis, the compensation of the Companys named executive officers for the year ended December 31, 2024.

11

To authorize the directors to allot shares in the company.

12

To approve the disapplication of statutory pre-emption rights. (SPECIAL RESOLUTION)