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Form of Proxy

ARCTURUS THERAPEUTICS HOLDINGS INC.

Notes

No. Proposition For Against Abstain
1

DIRECTOR Dr. Peter Farrell

2

DIRECTOR Joseph E. Payne

3

DIRECTOR Andy Sassine

4

DIRECTOR James Barlow

5

DIRECTOR Dr. Edward W. Holmes

6

DIRECTOR Dr. Magda Marquet

7

DIRECTOR Dr. Jing L. Marantz

8

DIRECTOR Dr. John Markels

9

DIRECTOR Dr. Moncef Slaoui

10

Approval, by non-binding advisory vote, of the resolution approving the Companys Named Executive Officer compensation, as provided in Proposal Number 2 of the Proxy Statement.

11

Ratification of the appointment of Deloitte & Touche LLP as the Companys independent registered public accounting firm for the fiscal year ending December 31, 2025.