| No. |
Proposition |
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For |
Against |
Abstain |
| 1 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Iain Dukes, D. Phil. |
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| 2 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Athena Countouriotis, M.D. |
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| 3 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Ryan Maynard |
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| 4 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Wayne P. Rothbaum |
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| 5 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Frederick G. Vogt, Ph.D., J.D. |
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| 6 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Michael Weiser, M.D., Ph.D. |
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| 7 |
Election of Director to serve until the 2026 Annual Meeting of Stockholders: Wendy Yarno |
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| 8 |
To approve, by non-binding advisory vote, the compensation of our named executive officers. |
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| 9 |
To ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2025. |
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| 10 |
To approve an amendment to our 2018 Equity Incentive Plan to increase the number of shares of the Companys common stock authorized for issuance thereunder by 12,500,000 shares. |
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| 11 |
To approve an amendment to our 2020 Employee Stock Purchase Plan to increase the number of shares of the Companys common stock authorized for issuance thereunder by 1,000,000 shares. |
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