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Form of Proxy

TWILIO INC.

Notes

No. Proposition For Against Abstain
1

DIRECTOR Donna Dubinsky

2

DIRECTOR Deval Patrick

3

DIRECTOR Miyuki Suzuki

4

To ratify the appointment of KPMG LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2025.

5

To approve, on a non-binding advisory basis, the compensation of our named executive officers.

6

To approve a management proposal to amend our certificate of incorporation to declassify the board of directors.

7

To approve a management proposal to amend our certificate of incorporation to eliminate supermajority voting provisions.

8

To approve a management proposal to amend our certificate of incorporation to remove inoperative provisions, including references to Class B common stock, and update certain other miscellaneous provisions.