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Form of Proxy

BEAM THERAPEUTICS INC.

Notes

No. Proposition For Against Abstain
1

Election of Class II Director for three-year terms ending at our Annual Meeting of Stockholders to be held in 2028: Mark Fishman, M.D.

2

Election of Class II Director for three-year terms ending at our Annual Meeting of Stockholders to be held in 2028: Carole Ho, M.D.

3

Election of Class II Director for three-year terms ending at our Annual Meeting of Stockholders to be held in 2028: Kathleen Walsh

4

Ratify the appointment of Deloitte & Touche LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2025.

5

Approve, on an advisory basis, the compensation of our named executive officers.