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Form of Proxy

PRECISION BIOSCIENCES, INC.

Notes

No. Proposition For Against Abstain
1

DIRECTOR Kevin J. Buehler

2

DIRECTOR Share Lisa Piré

3

Ratification of the appointment of Deloitte & Touche LLP as Precisions independent registered public accounting firm for 2025.

4

Approval, on an advisory (non-binding) basis, of the compensation of our named executive officers (commonly referred to as the say-on-pay vote).

5

Approval, on an advisory (non-binding) basis, of the frequency of future say-on-pay votes.

6

Approval of an amendment to our Certificate of Incorporation to reflect changes in Delaware law regarding officer exculpation.