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Form of Proxy

ILLUMINA, INC.

Notes

No. Proposition For Against Abstain
1

Election of Director: Frances Arnold, Ph.D.

2

Election of Director: Caroline D. Dorsa

3

Election of Director: Robert S. Epstein, M.D.

4

Election of Director: Scott Gottlieb, M.D.

5

Election of Director: Gary S. Guthart, Ph.D.

6

Election of Director: Keith A. Meister

7

Election of Director: Anna Richo

8

Election of Director: Philip W. Schiller

9

Election of Director: Susan E. Siegel

10

Election of Director: Jacob Thaysen, Ph.D.

11

Election of Director: Scott B. Ullem

12

To ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 28, 2025.

13

To approve, on an advisory basis, the compensation of the named executive officers as disclosed in the Proxy Statement.

14

To approve the Second Amended and Restated 2015 Stock and Incentive Plan of Illumina, Inc.